Description
Arginine Alpha-Ketoglutarate (AAKG) is a 2:1 mixture of the amino arginine and alpha-ketoglutarate. Alpha-ketoglutarate (AKG) is the deaminated carbon skeleton (missing the amino group) of the amino s glutamic (aka glutamate) and glutamine. Alpha-ketoglutarate is also an intermediate in the Kreb's cycle, a set of metabolic processes involved in energy (ATP) production from fats and carbohydrates, as well as amino metabolism. As such, AKG is an important metabolic link between cellular energy production and protein metabolism. In states of high protein intake or simply during normal protein turnover, AKG receives the amino (nitrogen containing) groups from amino s, forming glutamate, which then contributes to the urea cycle (where urea is produced and eventually lost in the urine). AKG can also be used in amination reactions to generate arginine (as well as proline and histidine). Mixing AKG with arginine would therefore favor less deamination of arginine, preserving it and prolonging its effects. In states of impaired protein metabolism such as dialysis, supplementing with AKG by itself positively affects amino handling. AKG also improves intestinal health (perhaps by assisting in glutamine metabolism, which fuels the immune system of the gut, improves immune function during physiological trauma (e.g., burns) and positively affects protein turnover in a malnourished or hypocaloric (negative caloric balance) state. Pure AAKG 2:1 Powder. In-house lab tested for purity. Non-GMO, , and vegan. Product includes one 125g or 250g jar of AAKG 2:1 Powder. * , treat, cure or prevent any . Country of Origin: United States of America Manufacturer/Importer/Packed By: Nootropics Depot
