Description
What is Sarcosine?
Sarcosine is also known as N-Methylglycine and Methylglycine. Sarcosine is synthesized from the glycine N-Methyltransferase (GMNT) enzyme which utilizes a methyl group from S-Adenosyl methionine and donates it to glycine. This process creates Sarcosine and S-adenosylhomocysteine.
Sarcosine shares properties with glycine and D-serine but its effects are weaker. However, sarcosine is more reliably absorbed by the body than D-serine so a smaller more practical dose of sarcosine would achieve the same effects compared to glycine or D-serine. Sarcosine metabolism is achieved through pipecolic acid oxidase (PIPOX) or sarcosine dehydrogenase (SARDH) enzymes. PIPOX and SARDH convert sarcosine into glycine.
Sarcosine Benefits and Uses